药用高分子材料 中文导读版
作者：刘黎，郭圣荣 主编
出版时间：2015年版
内容简介
《Polymers for Pharmaceutical Application：药用高分子材料（中文导读版）》是编者总结近十年的教学经验，从大量英文原版文献和书籍中选取适合教学大纲要求的内容编写而成，并对关键知识点配以中文导读，便于学生阅读和理解。全书共分6章，主要内容如下：第一章为药用辅料概述；第二章为高分子材料简介；第三章、第四章分别介绍选材于《Handbook of Pharmaceutical Excipients》（Fourth Edition，edited by Raymond C Rowe，Paul J Sheskey and Paul J Weller）中的天然高分子辅料和合成高分子辅料；第五章介绍现代药物输送系统研发中涉及的生物可降解高分子材料；第六章介绍几类新型的高分子药物输送体系，包括：自组装高分子和纳米制剂、药用水凝胶、高分子-药物轭合物、高分子基因载体。
目录
Chapter 1. Introduction to Pharmaceutical Excipients
药用辅料概述
1.1 Definition of pharmaceutical excipients
1.2 What are excipients doing in medicines?
1.3 Quality and safty of excipients
1.4 Relationship between polymers and pharmaceutical excipients
1.5 Specific notes for polymers used in drug delivery system
本章中文导读
References
Chapter 2. Introduction to Polymers
高分子材料概述
2.1 What are polymers?
2.2 Polymer structure and morphology
2.2.1 Molecular weight
2.2.2 Configuration and conformation
2.2.3 Chain structure
2.2.4 Crystalline
2.3 Synthesis
2.3.1 Addition polymerization
2.3.2 Condensation polymerization
2.3.3 Cross-linking reaction
2.4 Characteristic properties of polymers
2.4.1 Thermal properties
2.4.2 Mechanical properties
2.4.3 Viscoelastic properties
2.5 Characterization techniques
2.5.1 Determination of molecular weight
2.5.2 Determination of structure
2.5.3 Differential scanning calorimetry
2.6 Fabrication and processing
2.6.1 Injection molding
2.6.2 Extrusion
2.6.3 Spinning
本章中文导读
References
Chapter 3. Natural Polymers as Pharmaceutical Excipients
天然来源的药用高分子辅料
3.1 Starch and its derivates
3.1.1 Starch
3.1.2 Pregelatinized starch
3.1.3 Dextrin
3.1.4 Cyclodextrin
3.1.5 Sodium carboxymethyl starch
本节中文导读
3.2 Cellulose and its derivates
3.2.1 Microcrystalline cellulose
3.2.2 Powdered cellulose
3.2.3 Methylcellulose
3.2.4 Ethylcellulose
3.2.5 Hydroxyethyl cellulose
3.2.6 Hydroxypropyl cellulose
3.2.7 Hydroxypropyl methylcellulose
3.2.8 Carboxymethylcellulose sodium
3.2.9 Carboxymethylcellulose calcium
3.2.10 Cellulose acetate phthalate
本节中文导读
3.3 Other natural polymers in pharmaceutics
3.3.1 Chitin/chitosan
3.3.2 Alginate and sodium/calcium alginate
3.3.3 Acacia
3.3.4 Xanthan gum
3.3.5 Gelatin
3.3.6 Albumin
本节中文导读
References
Chapter 4. Synthetic Polymers as Pharmaceutical Excipients
合成的药用高分子敷料
4.1 Polymers based on polyvinyl
4.1.1 Polyvinyl alcohol
4.1.2 Polymethacrylates
4.1.3 Polyvinylpyrrolidone (Povidone)
4.1.4 Crospovidone
4.1.5 Carbomer
本节中文导读
4.2 Polymers based on polyether
4.2.1 Polyethylene glycol
4.2.2 Poloxamer
4.2.3 Polysorbates
本节中文导读
References
Chapter 5. Novel Synthetic Biodegradable Polymers as Drug
Delivery Carrier
新型可生物降解的合成药用高分子材料
5.1 Introduction
5.2 Polymers based on polyester
5.2.1 Poly(lactic acid) and poly(lactic-co-glycolic acid) copolymers
5.2.2 Polycaprolactone
5.2.3 Poly(β-hydroxybutyrate)
5.3 Other biodegradable polymers
5.3.1 Poly(orthoesters)
5.3.2 Poly(phosphate esters)
5.3.3 Polyanhydrides
5.3.4 Poly(amino acids)
5.3.5 Polyphosphazenes
本章中文导读
References
Chapter 6. Advanced Applications of Functional Polymer in Drug Delivery
功能高分子材料在药物输送中的应用进展
6.1 Hydrogels for pharmaceutical application
6.1.1 Introduction
6.1.2 Preparation of hydrogels
6.1.3 Properties of hydrogels
6.1.4 Pharmaceutical applications of hydrogels
本节中文导读
6.2 Polymer-based nanomedicine and self-assemblying polymers
6.2.1 Introduction to nanomedicine
6.2.2 Micellation of self-assemblying polymers
6.2.3 Biological significance of polymeric micelles
6.2.4 Drug release from polymeric micelles
6.2.5 Examples of polymeric micelles for drug delivery
本节中文导读
6.3 Polymer-drug conjugates
6.3.1 Introduction
6.3.2 Design and development of polymer-drug conjugates
6.3.3 Examples for polymer-drug conjugates
本节中文导读
6.4 Polymers for gene delivery
6.4.1 Introduction to gene delivery
6.4.2 Polymeric vectors
本节中文导读
References
